1. What are the causes of Psoriatic arthritis ?
Like psoriasis and other chronic inflammatory rheumatic diseases, psoriatic arthritis is caused by a combination of genetic predisposition and environmental factors (e.g., stress, physical or emotional trauma, or infection). The immune system reacts abnormally and attacks the joint tissues as if they were foreign bodies. This autoimmune reaction causes local inflammation, which leads to pain, stiffness and swelling of the joints and, in the long term, to damage.But other non-genetic risk factors for psoriatic arthritis are suspected: obesity, type 2 diabetes, hypertension, metabolic syndrome and, of course, psoriasis, especially in its severe and extensive forms, as well as those affecting the scalp, nails or the intergluteal fold.It’s not completely clear why the immune system attacks healthy tissue, but it appears likely that both genetic and environmental factors play a role.
However, having a genetic predisposition does not necessarily mean that you will develop psoriasis or psoriatic arthritis.
